We explain the most typical Unintended effects of this remedy listed here. We also include things like some which are fewer frequent.  This metabolite seems to act by inhibiting DNA polymerase alpha, ribonucleotide reductase and DNA primase, Consequently inhibiting DNA synthesis. The system

 5c–d). CX-5461-mediated S33 phosphorylation of RPA was impartial on the cell cycle phase and was not restricted into the nucleoli in HR-deficient cells. So, the development of ssDNA buildings in CX-5461 addressed cells may lead to replication fork stalling and ATR activation with HRD exa